Hypertension and sleep apnea: The Deadly Duo

Deadly duo

An astonishing one-third of the world’s population is infected with the bacterium that causes tuberculosis (TB), Mycobacterium tuberculosis. In most people it remains inactive or latent but in about 10% of people an active case of TB disease will develop within their lifetime. Simple antibiotics can prevent and treat most of these cases, yet 8-10 million people develop an active TB infection an...

HIV & TB “ The Deadly Duo ”

WHO estimates that more than 7 million people, 98% of whom are in the developing world are co-infected with HIV and TB. The situation is explosive, leading to unprecedented public health crises. Both diseases are devastating but the devastation of the TB /HIV co-epidemic surpasses the devastation of either disease on its own. An estimated 1.4 million new cases of HIV-TB occurred in 2008, repres...

Sleep apnea and hypertension.

Obstructive sleep apnea and hypertension.

There has long been a recognized link between obstructive sleep apnea (OSA) and the cardiovascular system, no aspect of which has been more studied than blood pressure. Research in OSA has not only demonstrated dysregulation of homeostatic cardiovascular mechanisms but also has furthered our understanding of blood pressure regulatory control. Acute nocturnal blood pressure elevations associated...

Hypertension and obstructive sleep apnea

Obstructive sleep apnea (OSA) is increasingly being recognized as a major health burden with strong focus on the associated cardiovascular risk. Studies from the last two decades have provided strong evidence for a causal role of OSA in the development of systemic hypertension. The acute physiological changes that occur during apnea promote nocturnal hypertension and may lead to the development...